Mental versus physical stress, QT prolongation, and the autonomic nervous system.
نویسندگان
چکیده
منابع مشابه
QT interval and dispersion in primary autonomic failure.
OBJECTIVE To investigate the role of the autonomic nervous system in determining QT interval and dispersion. PATIENTS AND METHODS 32 patients with chronic primary (idiopathic) autonomic failure (19 men, mean age 60 years) and 21 normal controls (11 men, mean age 59) without symptoms of ischaemic heart disease were studied retrospectively. Autonomic failure was diagnosed by a combination of sy...
متن کاملDetermination of sensitivity and specificity of QT interval in ECG of diabetic patients for ndiagnosis of cardiac autonomic neuropathy
one of the important complications of diabetes mellitus that physicians pay less attention to is diabetic autonomic neuropathy(DNA) ,especially cardiac autonomic neuropathy (CAN).this has a poor prognosis and is accompanied by sudden death risk,recently several investigations that were carried out for CAN detection ,suggested that QT-interval prolongation in these patients is an important diagn...
متن کاملParoxetine‐induced QTc prolongation
There have been only two previous reports of paroxetine-induced corrected QT (QTc) prolongation on electrocardiogram (ECG). Here, we report a 43-year-old woman with QTc prolongation (476 ms). She had taken 50 mg of paroxetine for 17 days. Three days after discontinuation of paroxetine, QTc returned to within the normal limits (396 ms). Paroxetine blocks the human ether-a-go-go-related gene (HER...
متن کاملModulation of QT interval during autonomic nervous system blockade in humans.
BACKGROUND It is thought that the autonomic nervous system modulates QT interval, but traditional autonomic blockade combining propranolol and atropine has produced conflicting results. We used the alternative approach of interrupting neurotransmission at the level of autonomic ganglia to determine its effect on the QT interval. METHODS AND RESULTS We infused trimethaphan at increasing doses ...
متن کاملEvaluation of QT interval length, QT dispersion and myocardial m-iodobenzylguanidine uptake in insulin-dependent diabetic patients with and without autonomic neuropathy.
1. An association has been reported between QT interval abnormalities and cardiovascular autonomic neuropathy in diabetic patients. The QT interval abnormalities reflect local inhomogeneities of ventricular recovery time and may be related to an imbalance in cardiac sympathetic innervation. Sympathetic innervation of the heart can be visualized and quantified by single-photon emission-computed ...
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عنوان ژورنال:
- Circulation
دوره 101 22 شماره
صفحات -
تاریخ انتشار 2000